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In Vivo Fate Analysis Reveals the Multipotent and Self-Renewal Capacities of Sox2+ Neural Stem Cells in the Adult Hippocampus

Cell stem cell · 2007 · Vol. 1(5) · pp. 515–528
Hoonkyo SuhAntonella ConsiglioJasodhara RayToru SAWAIKevin A. D’AmourFred H. Gage
Neurogenesis and neuroplasticity mechanismsMicroRNA in disease regulationNeuroinflammation and Neurodegeneration MechanismsSOX2BiologyNeurogenesisNeural stem cellSubgranular zoneProgenitor cellCell biologyStem cellMultipotent Stem CellPopulation

MeSH terms

AnimalsAstrocytesCell DifferentiationCells, CulturedDNA-Binding ProteinsPhysical ExertionMice, Inbred C57BLMice, TransgenicMicroscopy, FluorescenceNeuronsPromoter Regions, GeneticRetroviridaeTime FactorsTranscription FactorsLentivirus

Funding

  • American Society for Pharmacology and Experimental Therapeutics
  • University of Nebraska Medical Center
  • National Science Council
  • Defense Advanced Research Projects Agency
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