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Small “flat adenoma” of the large bowel with special reference to its clinicopathologic features

Diseases of the Colon & Rectum · 1985 · Vol. 28(10) · pp. 847–851

Tetsuichiro Muto✉(The University of Tokyo)J Kamiya(The University of Tokyo)T. Sawada(The University of Tokyo)Fumio Konishi(The University of Tokyo)Kenichi Sugihara(The University of Tokyo)Yoshiro Kubota(The University of Tokyo)Miki Adachi(The University of Tokyo)S. Agawa(The University of Tokyo)Y. Saito(The University of Tokyo)Y Morioka(The University of Tokyo)Taveesin Tanprayoon(Chulalongkorn University)

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Abstract

Thirty-three small "flat adenomas," not more than 1 cm in diameter, were collected from surgically and colonoscopically removed specimens, and their colonoscopic and histologic characteristics were described. There were 14 adenomas with mild atypia, five with moderate atypia, 14 with severe atypia (or focal carcinoma limited to the mucosa). The grade of atypia seems to increase with the size of lesions, and these lesions were assumed to play an important role in the adenoma-carcinoma sequence. The importance of recognizing the presence of these small "flat adenomas" in everyday practice is stressed.

Gastrointestinal disorders and treatments Gastric Cancer Management and Outcomes Gastrointestinal Tumor Research and TreatmentAtypiaMedicineAdenomaSurgical oncologyCarcinomaNuclear atypiaColorectal surgeryPathologyRadiologyGeneral surgery