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An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons

Toxicology and Applied Pharmacology · 2003 · Vol. 189(3) · pp. 233–246
Esther BrandonChristiaan D RaapIrma MeijermanJos H. BeijnenJan H.M. Schellens
Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and ProtectionDrug Transport and Resistance MechanismsBiotransformationIn vivoS9 fractionIn vitroDrug metabolismMicrosomeHuman liverIn vitro toxicologyLiver cellDrug

MeSH terms

AnimalsBiotransformationDrug Evaluation, PreclinicalPharmaceutical PreparationsHumansLiverMicrosomes, Liver
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