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Expression of Prostate‐Specific Membrane Antigen in Normal and Malignant Human Tissues

World Journal of Surgery · 2006 · Vol. 30(4) · pp. 628–636
Yoshihisa KinoshitaKatsuyuki KuratsukuriSteve LandasKatsumi ImaidaPeter M. RovitoChing Y. WangGabriel P. Haas

Abstract

These findings demonstrate that PSMA is widely distributed in normal tissues, and, depending on the tumors, its expression is up- or down-regulated, or unchanged. The broad distribution of PSMA may make it suitable for the diagnosis and therapy of a wide variety of tumors.

Prostate Cancer Treatment and ResearchRadiopharmaceutical Chemistry and ApplicationsImmunotherapy and Immune ResponsesProstatePathologyMedicineImmunohistochemistryLungUrinary bladderProstate cancerAdenocarcinomaPCA3Cancer

MeSH terms

Antigens, SurfaceFemaleHumansMaleNeoplasmsProstateProstatic NeoplasmsReference ValuesTissue DistributionTumor Cells, CulturedBiomarkers, TumorGlutamate Carboxypeptidase II

Funding

  • National Institutes of Health
Citations
375
FWCI
7.56
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References
41
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