reviewTop 1% cited
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future
Oncogene · 2002 · Vol. 21(35) · pp. 5427–5440
Manel Esteller✉(Centro Nacional de Epidemiología)
Epigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancerDNA methylationBiologyEpigeneticsCarcinogenesisCpG siteCancer epigeneticsTumor suppressor geneCancer researchGene silencingMethylation
MeSH terms
Genetic MarkersHumansNeoplasmsPromoter Regions, GeneticGene Expression Regulation, NeoplasticGenes, Tumor SuppressorCpG IslandsDNA MethylationGene Silencing
Funding
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Citations
1,222
FWCI
19.18
field-weighted impact
References
96
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100%
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References
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
Nature Genetics · 1998 · 2,718 citations
Cancer-epigenetics comes of age
Nature Genetics · 1999 · 2,354 citations
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Proceedings of the National Academy of Sciences · 1996 · 5,649 citations
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
Human Molecular Genetics · 2001 · 941 citations
The DNA methylation paradox
Trends in Genetics · 1999 · 655 citations
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