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Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

Cancer Letters · 2008 · Vol. 266(1) · pp. 37–52
Masuko Ushio‐FukaiYoshimasa Nakamura
Angiogenesis and VEGF in CancerCancer, Hypoxia, and MetabolismNanoplatforms for cancer theranosticsAngiogenesisNADPH oxidaseNOX1NOX4Cell biologyBiologyVascular endothelial growth factorReactive oxygen speciesVascular endothelial growth factor ACancer research

MeSH terms

DietHumansModels, BiologicalNeoplasmsNeovascularization, PathologicSuperoxide DismutaseSignal TransductionDrug Delivery SystemsReactive Oxygen SpeciesNADPH OxidasesAngiogenesis InhibitorsVascular Endothelial Growth Factor Receptor-2Vascular Endothelial Growth Factor A

Funding

  • National Institutes of Health
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Vascular protection by dietary polyphenols
European Journal of Pharmacology · 2004 · 565 citations
Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2004 · 768 citations
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