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MULTICENTER RANDOMIZED TRIAL COMPARING TACROLIMUS (FK506) AND CYCLOSPORINE IN THE PREVENTION OF RENAL ALLOGRAFT REJECTION1

Transplantation · 1997 · Vol. 64(3) · pp. 436–443
A. David MayerJan DmitrewskiJean-Paul SquiffletTatjana BesseB. GrabenseeBarbara C. KleinFriedrich W. EiglerUwe HeemannR PichlmayrMatthias BehrendYves VanrenterghemJ DonckJohannes van HooffMaarten H. L. ChristiaansJ.M. MoralesAmado AndrésRobert W. JohnsonColin D. ShortB. BuchholzNikola RehmertW. LandStefan SchleibnerJohn ForsytheDavid TalbotHans‐H. NeumayerI. HäuserBo-G ran EriczonChristina Brattstr mKerstin ClaessonFerdinand M hlbacherErich Pohanka

Abstract

The significant reduction in the incidence of episodes of allograft rejection observed with tacrolimus therapy may have important long-term implications given the prognostic influence of rejection on graft survival.

Renal Transplantation Outcomes and TreatmentsPharmacological Effects and Toxicity StudiesOral and gingival health researchMedicineTacrolimusInternal medicineTransplantationAzathioprineGastroenterologyCiclosporinDiabetes mellitusRandomized controlled trialSurgery

MeSH terms

AdolescentAdultAgedDose-Response Relationship, DrugFemaleGraft RejectionHumansImmunosuppressive AgentsMaleMiddle AgedTransplantation, HomologousKidney TransplantationTacrolimusCyclosporine
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MULTICENTER RANDOMIZED TRIAL COMPARING TACROLIMUS (FK506) AND CYCLOSPORINE IN THE PREVENTION OF RENAL ALLOGRAFT REJECTION1 · Scinovex