articleTop 1% cited

Clustering of Hepatotoxins Based on Mechanism of Toxicity Using Gene Expression Profiles

Toxicology and Applied Pharmacology · 2001 · Vol. 175(1) · pp. 28–42

Jeffrey F. Waring✉(Abbott Fund)Robert A. Jolly(Abbott Fund)Rita Ciurlionis(Abbott Fund)Pek Yee Lum(Rosetta Stone (United States))Jens Præstgaard(Abbott Fund)David C. Morfitt(Abbott Fund)Bruno Buratto(Abbott Fund)Chris Roberts(Rosetta Stone (United States))Eric E. Schadt(Rosetta Stone (United States))Roger G. Ulrich(Abbott Fund)

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Gene expression and cancer classification Computational Drug Discovery Methods Molecular Biology Techniques and ApplicationsToxicogenomicsGene expressionDNA microarrayHepatotoxinMicroarrayGeneBiologyGene chip analysisGene expression profilingPharmacology

MeSH terms

AmiodaroneAnimalsCarbon TetrachlorideDiethylnitrosamineLiverMalePhylogenyToxins, BiologicalGene ExpressionRats, Sprague-DawleyPropanolsChlorodiphenyl (54% Chlorine)Gene Expression ProfilingRats

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378

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14.70

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99%

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References

Casarett and Doull's Toxicology: The Basic Science of Poisons

Annals of Internal Medicine · 1992 · 3,307 citations

Systematic variation in gene expression patterns in human cancer cell lines

Nature Genetics · 2000 · 2,090 citations

Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays

Proceedings of the National Academy of Sciences · 1999 · 4,201 citations

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

Science · 1999 · 11,587 citations

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