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Oligosaccharides in human milk during different phases of lactation

Acta Paediatrica · 1999 · Vol. 88(s430) · pp. 89–94
GV CoppaPaolo PieraniLucia ZampiniI CarloniAntonio CarlucciOrazio Gabrielli

Abstract

Twenty-one oligosaccharides of human milk were quantified by high-performance anion-exchange chromatography. Milk samples were collected from 18 mothers during the first 3 mo of lactation. The data show that the highest amount of all oligosaccharides is present at day 4 postpartum (20 g l(-1)) and then decreases by about 20% at day 30 of lactation. The protective role played by these substances against different infectious agents, in different organs and systems of the breastfed baby, is emphasized.

Infant Nutrition and HealthBreastfeeding Practices and InfluencesNeonatal Respiratory Health ResearchLactationMedicineBreast milkOligosaccharideBreast feedingPhysiologyAnimal scienceFood sciencePregnancyBiochemistry

MeSH terms

AdultChromatography, High Pressure LiquidChromatography, Ion ExchangeFemaleHumansInfantInfant, NewbornLactationLongitudinal StudiesMilk, HumanOligosaccharidesSensitivity and SpecificityTime FactorsPostpartum Period
Citations
295
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25
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92%
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References
Biological functions of oligosaccharides in human milk
Acta Paediatrica · 1993 · 335 citations
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