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Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review
AIDS · 2006 · Vol. 20(17) · pp. 2165–2174
Todd T. Brown✉(Johns Hopkins University)Roula Qaqish(Abbott Fund)
Abstract
The prevalence of osteoporosis in HIV-infected individuals is more than three times greater compared with HIV-uninfected controls. ART-exposed and PI-exposed individuals had a higher prevalence of reduced BMD and osteoporosis compared with their respective controls. The influence of other disease and treatment variables on these estimates could not be determined.
HIV-related health complications and treatmentsPharmacological Effects and Toxicity StudiesBone and Joint DiseasesMedicineOsteoporosisOsteopeniaOdds ratioInternal medicineMeta-analysisBone mineralConfidence interval
MeSH terms
AdultAgedBone Diseases, MetabolicCross-Sectional StudiesFemaleHumansMaleMiddle AgedProtease InhibitorsBone DensityHIV InfectionsAntiretroviral Therapy, Highly Active
Citations
921
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25.82
field-weighted impact
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54
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100%
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Citations per year
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The Lancet Infectious Diseases · 2015 · 907 citations
References
Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>
JAMA · 2000 · 20,480 citations
Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy
AIDS · 2000 · 541 citations
Consensus development conference: Diagnosis, prophylaxis, and treatment of osteoporosis
The American Journal of Medicine · 1993 · 2,859 citations
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