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Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome

Archives of Dermatology · 2000 · Vol. 136(3) · pp. 323–7

I. García‐Doval✉(Complejo Hospitalario de Pontevedra)Laurence Le CleachHélène BocquetXose-Luis OteroJean‐Claude Roujeau

Abstract

Prompt withdrawal of drug(s) that are suspected to cause SJS or TEN may decrease mortality. Prompt withdrawal of causative drugs should be a priority when blisters or erosions appear in the course of a drug eruption.

Drug-Induced Adverse Reactions Urticaria and Related Conditions Autoimmune Bullous Skin DiseasesToxic epidermal necrolysisMedicineOdds ratioConfidence intervalDrug withdrawalConfoundingIntensive care unitPediatricsInternal medicineDermatology

MeSH terms

AdultAgedAnimalsPharmaceutical PreparationsFemaleHalf-LifeHumansLongitudinal StudiesMaleMiddle AgedPrognosisStevens-Johnson SyndromeTime FactorsLogistic ModelsOdds Ratio

Citations

485

FWCI

13.95

field-weighted impact

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99%

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International<scp>Con</scp>sensus on drug allergy