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Unusual brain growth patterns in early life in patients with autistic disorder

Neurology · 2001 · Vol. 57(2) · pp. 245–254
Eric CourchesneChristina M. KarnsHarvey DavisR. ZiccardiRuth A. CarperZachary TigueHeather J. ChisumPamela MosesKaren PierceCatherine LordA. J. LincolnSenia PizzoLaura SchreibmanRichard HaasNatacha AkshoomoffR Courchesne

Abstract

Abnormal regulation of brain growth in autism results in early overgrowth followed by abnormally slowed growth. Hyperplasia was present in cerebral gray matter and cerebral and cerebellar white matter in early life in patients with autism.

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental DisordersCongenital heart defects researchAutismWhite matterPsychologyCerebellumDevelopmental disorderBrain sizeGrey matterCerebellar vermisGray (unit)Magnetic resonance imaging

MeSH terms

AdolescentAutistic DisorderBrainChildChild, PreschoolHumansMagnetic Resonance ImagingMaleTime Factors
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