articleTop 1% cited
Unusual brain growth patterns in early life in patients with autistic disorder
Neurology · 2001 · Vol. 57(2) · pp. 245–254
Eric Courchesne✉(Center for Neurosciences)Christina M. Karns(Center for Neurosciences)Harvey Davis(Center for Neurosciences)R. Ziccardi(Center for Neurosciences)Ruth A. Carper(Center for Neurosciences)Zachary Tigue(Center for Neurosciences)Heather J. Chisum(Center for Neurosciences)Pamela Moses(Center for Neurosciences)Karen Pierce(Center for Neurosciences)Catherine Lord(Center for Neurosciences)A. J. Lincoln(Center for Neurosciences)Senia Pizzo(Center for Neurosciences)Laura Schreibman(Center for Neurosciences)Richard Haas(Center for Neurosciences)Natacha Akshoomoff(Center for Neurosciences)R Courchesne(Center for Neurosciences)
Abstract
Abnormal regulation of brain growth in autism results in early overgrowth followed by abnormally slowed growth. Hyperplasia was present in cerebral gray matter and cerebral and cerebellar white matter in early life in patients with autism.
Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental DisordersCongenital heart defects researchAutismWhite matterPsychologyCerebellumDevelopmental disorderBrain sizeGrey matterCerebellar vermisGray (unit)Magnetic resonance imaging
MeSH terms
AdolescentAutistic DisorderBrainChildChild, PreschoolHumansMagnetic Resonance ImagingMaleTime Factors
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