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A RANDOMIZED DOUBLE-BLIND, MULTICENTER PLASMA CONCENTRATION CONTROLLED STUDY OF THE SAFETY AND EFFICACY OF ORAL MYCOPHENOLATE MOFETIL FOR THE PREVENTION OF ACUTE REJECTION AFTER KIDNEY TRANSPLANTATION1

Transplantation · 1999 · Vol. 68(2) · pp. 261–266

Abstract

MPA Cpredose and MPA AUC are significantly related to the incidence of biopsy-proven rejection after kidney transplantation, whereas MMF dose is significantly related to the occurrence of adverse events.

Renal Transplantation Outcomes and TreatmentsOrgan Transplantation Techniques and OutcomesOrgan Donation and TransplantationMycophenolateMedicineMulticenter studyDouble blindRandomized controlled trialInternal medicineTransplantationAlternative medicinePathology

MeSH terms

Acute DiseaseAdministration, OralAdultDrug Therapy, CombinationFemaleGraft RejectionGraft SurvivalHumansImmunosuppressive AgentsKidneyMaleMiddle AgedMycophenolic AcidOpportunistic InfectionsPharmacokinetics
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