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Diversity of Bacteria at Healthy Human Conjunctiva

Investigative Ophthalmology & Visual Science · 2011 · Vol. 52(8) · pp. 5408–5408
Qunfeng DongJennifer M. BrulcAlfonso IovienoBrandon BatesAaron GaroutteDarlene MillerKashi V. RevannaXiang GaoDionysios A. AntonopoulosVladlen Z. SlepakValery I. Shestopalov

Abstract

The first DNA sequencing-based survey of bacterial population at the conjunctiva have revealed an unexpectedly diverse microbial community. All analyzed samples contained ubiquitous (core) genera that included commensal, environmental, and opportunistic pathogenic bacteria.

Ocular Infections and TreatmentsOcular Surface and Contact LensGut microbiota and healthBiologyDNA sequencingMicrobiomeProteobacteriaMicrobiology16S ribosomal RNAGeneticsBacteriaDNA

MeSH terms

AdultBacteriaConjunctivaDNA, BacterialHumansMaleMiddle AgedPilot ProjectsRNA, Ribosomal, 16SGene LibraryPolymerase Chain ReactionSequence Analysis, DNAGenes, rRNAMetagenomeHigh-Throughput Nucleotide Sequencing

Funding

  • Research to Prevent Blindness
  • National Institutes of Health
  • Argonne National Laboratory
Citations
389
FWCI
9.06
field-weighted impact
References
67
Percentile
98%
vs. same field & year
Citations per year
References
Bacterial Diversity in Human Subgingival Plaque
Journal of Bacteriology · 2001 · 2,007 citations
Skin microbiota: a source of disease or defence?
British Journal of Dermatology · 2008 · 965 citations
Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy
Applied and Environmental Microbiology · 2007 · 20,269 citations
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