review Open AccessTop 1% cited
Molecular mechanisms of N -acetylcysteine actions
Cellular and Molecular Life Sciences · 2003 · Vol. 60(1) · pp. 6–20
Muhammad Zafarullah✉(Hôpital Notre-Dame)W. Q. Li(Hôpital Notre-Dame)Judith Sylvester(Hôpital Notre-Dame)Mushtaq Ahmad(Emory University)
Genomics, phytochemicals, and oxidative stressCurcumin's Biomedical ApplicationsVitamin C and Antioxidants ResearchOxidative stressProinflammatory cytokineReactive oxygen speciesAcetylcysteineTranscription factorSignal transductionKinaseCell biologyCancer researchp38 mitogen-activated protein kinases
MeSH terms
AcetylcysteineAnimalsAntioxidantsCell SurvivalHumansLiverMuscle, Smooth, VascularOxidation-ReductionSignal TransductionFree Radical ScavengersNF-kappa BApoptosisReactive Oxygen SpeciesOxidative StressMitogen-Activated Protein Kinases
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References
H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.
The EMBO Journal · 1993 · 1,317 citations
Antioxidant and redox regulation of gene transcription
The FASEB Journal · 1996 · 1,989 citations
An essential role for free radicals and derived species in signal transduction
The FASEB Journal · 1997 · 901 citations
Triggering and modulation of apoptosis by oxidative stress
Free Radical Biology and Medicine · 2000 · 1,325 citations
The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
Free Radical Biology and Medicine · 1989 · 1,760 citations
Oxidative Stress as a Mechanism of Chronic Cadmium-Induced Hepatotoxicity and Renal Toxicity and Protection by Antioxidants
Toxicology and Applied Pharmacology · 1999 · 468 citations
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