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Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine

Brain Research · 1975 · Vol. 92(2) · pp. 291–306

T.H. Svensson✉(Connecticut Mental Health Center)B.S. Bunney(Connecticut Mental Health Center)George K. Aghajanian(Connecticut Mental Health Center)

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Receptor Mechanisms and Signaling Neurotransmitter Receptor Influence on Behavior Ion channel regulation and functionClonidineLocus coeruleusAgonistChemistryMedian raphe nucleusDorsal raphe nucleusSerotonergicEndocrinologyInternal medicineSubstantia nigra

MeSH terms

AmphetamineAnimalsCerebral VentriclesClonidineFluorescenceHistocytochemistryHydroxydopaminesLysergic Acid DiethylamideMaleMembrane PotentialsNeuronsNorepinephrinePonsReceptors, AdrenergicSerotonin

Citations

1,017

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17.44

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103

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100%

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References

Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain

Brain Research · 1974 · 1,098 citations

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European Journal of Pharmacology · 1974 · 434 citations

Evidence for the existence of monoamine neurons in the central nervous system

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