articleTop 1% cited

Automated DNA sequencing of the human HPRT locus

Genomics · 1990 · Vol. 6(4) · pp. 593–608

Al Edwards✉(Baylor College of Medicine)Hartmut Voss(European Molecular Biology Laboratory)Peter Rice(European Molecular Biology Laboratory)Andrew B. Civitello(Baylor College of Medicine)Josef Stegemann(European Molecular Biology Laboratory)Christian Schwager(European Molecular Biology Laboratory)Juergen Zimmermann(European Molecular Biology Laboratory)Holger Erfle(European Molecular Biology Laboratory)C. Thomas Caskey(Baylor Genetics)Wilhelm Ansorge(European Molecular Biology Laboratory)

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Biochemical and Molecular Research Cytomegalovirus and herpesvirus research Adenosine and Purinergic SignalingContigBiologyGeneticsLocus (genetics)Alu elementDNA sequencingGeneExonRepeated sequenceHuman genome

MeSH terms

Amino Acid SequenceAutomationBase SequenceDNA, RecombinantExonsFluorometryGenesHumansHypoxanthine PhosphoribosyltransferaseMolecular Sequence DataNucleotide MappingRepetitive Sequences, Nucleic AcidRoboticsSoftware

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354

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Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families