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Progressive Increase of the Mutated Mitochondrial DNA Fraction in Kearns-Sayre Syndrome
Pediatric Research · 1990 · Vol. 28(2) · pp. 131–136
Nils‐Göran Larsson✉Elisabeth Holme(University of Gothenburg)B. Kristiansson(Sahlgrenska University Hospital)Anders Oldfors(University of Gothenburg)M. Tulinius(Sahlgrenska University Hospital)
Mitochondrial Function and PathologyMetabolism and Genetic DisordersGenetic Neurodegenerative DiseasesHeteroplasmyMitochondrial DNAKearns–Sayre syndromeMitochondrionBiologyMitochondrial diseaseMolecular biologyGeneticsPopulationGene
MeSH terms
AdolescentAdultBone MarrowChromosome DeletionChromosome MappingDNA, MitochondrialFemaleHumansKearns-Sayre SyndromeMaleMitochondria, MuscleMutationOphthalmoplegiaTime Factors
Citations
317
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6.73
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6
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98%
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References
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Analytical Biochemistry · 1983 · 25,153 citations
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