reviewTop 10% cited
NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development
Psychopharmacology · 2003 · Vol. 169(3-4) · pp. 215–233
John H. Krystal✉(VA Connecticut Healthcare System)Deepak Cyril D’Souza(Connecticut Mental Health Center)Daniel H. Mathalon(Connecticut Mental Health Center)Edward Perry(Connecticut Mental Health Center)Ayşenil Belger(University of North Carolina at Chapel Hill)Ralph E. Hoffman(Connecticut Mental Health Center)
Neuroscience and Neuropharmacology ResearchTryptophan and brain disordersTreatment of Major DepressionNMDA receptorGlutamatergicDisinhibitionSchizophrenia (object-oriented programming)NeurosciencePsychologyGlutamate receptorPsychosisAntagonistPhencyclidine
MeSH terms
AnimalsCerebral CortexCognitionHumansKetamineModels, NeurologicalNeural PathwaysSchizophreniaAntipsychotic AgentsReceptors, N-Methyl-D-AspartateExcitatory Amino Acid AntagonistsGlutamic Acid
Citations
531
FWCI
5.78
field-weighted impact
References
308
Percentile
98%
vs. same field & year
Citations per year
Cited by
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence
Molecular Psychiatry · 2004 · 2,025 citations
Schizophrenia, “Just the Facts”: What we know in 2008
Schizophrenia Research · 2008 · 402 citations
References
Pharmacologic effects of CI‐581, a new dissociative anesthetic, in man
Clinical Pharmacology & Therapeutics · 1965 · 747 citations
Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex
Journal of Neuroscience · 1997 · 1,794 citations
THE BRAIN’S RECORD OF AUDITORY AND VISUAL EXPERIENCE
Brain · 1963 · 1,227 citations
GABAergic Interneurons Implications for Understanding Schizophrenia and Bipolar Disorder
Neuropsychopharmacology · 2001 · 1,089 citations
Aripiprazole, a Novel Antipsychotic, Is a High-Affinity Partial Agonist at Human Dopamine D2 Receptors
Journal of Pharmacology and Experimental Therapeutics · 2002 · 915 citations
The reduced neuropil hypothesis: a circuit based model of schizophrenia
Biological Psychiatry · 1999 · 918 citations
Effects of Ketamine in Normal and Schizophrenic Volunteers
Neuropsychopharmacology · 2001 · 666 citations
Neuregulin 1 and Susceptibility to Schizophrenia
The American Journal of Human Genetics · 2002 · 1,659 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
