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Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936

Leukemia · 2003 · Vol. 17(12) · pp. 2257–2317

Jacques J. M. van Dongen✉(Erasmus MC)Anton W. Langerak(Erasmus MC)Monika Brüggemann(Universitäts Hautklinik Kiel)Paul Evans(University of Leeds)Michael Hummel(Freie Universität Berlin)F. Louise LavenderÉric Delabesse(Hôpital Necker-Enfants Malades)Frédéric Davi(Sorbonne Université)Ed Schuuring(Leiden University Medical Center)Ramón García‐Sánz(Complejo Hospitalario de Salamanca)J. Han van Krieken(Radboud University Nijmegen)J Droese(Universitäts Hautklinik Kiel)David González(Complejo Hospitalario de Salamanca)Christian Bastard(Centre Henri Becquerel)Helen WhiteMarcel Spaargaren(Academic Medical Center)Marcos González(Complejo Hospitalario de Salamanca)A Parreira(IPO Porto)J L SmithGareth J. Morgan(University of Leeds)Michael Kneba(Universitäts Hautklinik Kiel)Elizabeth Macintyre(Hôpital Necker-Enfants Malades)

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Lymphoma Diagnosis and Treatment Chronic Lymphocytic Leukemia Research T-cell and B-cell ImmunologyMultiplex ligation-dependent probe amplificationT-cell receptorHeteroduplexBiologyMolecular biologyPolymerase chain reactionMinimal residual diseaseImmunoglobulin heavy chainGene rearrangementImmunoglobulin light chain

MeSH terms

Chromosome AberrationsClone CellsEuropean UnionHumansImmunoglobulinsLymphoproliferative DisordersReceptors, Antigen, T-CellReference StandardsReproducibility of ResultsGene Rearrangement, T-LymphocytePolymerase Chain ReactionDNA PrimersNeoplasm, Residual

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