article Open AccessTop 1% cited
Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis
Critical Care · 2007 · Vol. 11(2) · pp. R49–R49
Fernando A. Bozza✉(Fundação Oswaldo Cruz)Jorge I. Salluh(Instituto Nacional do Câncer)André Miguel Japiassú(Fundação Oswaldo Cruz)Márcio Soares(Instituto Nacional do Câncer)Edson Assis(Fundação Oswaldo Cruz)Rachel N. Gomes(Fundação Oswaldo Cruz)Marcelo T. Bozza(Universidade Federal do Rio de Janeiro)Hugo C. Castro‐Faria‐Neto(Fundação Oswaldo Cruz)Patrı́cia T. Bozza(Fundação Oswaldo Cruz)
Abstract
In this exploratory analysis we demonstrated that use of a multiple cytokine assay platform allowed identification of distinct cytokine profiles associated with sepsis severity, evolution of organ failure and death.
Sepsis Diagnosis and TreatmentInflammation biomarkers and pathwaysRenal function and acid-base balanceMedicineSepsisMultiplexImmunologyDiseaseIntensive care medicineBioinformaticsInternal medicine
MeSH terms
AgedBiological AssayFemaleHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesROC CurveSeverity of Illness IndexShock, SepticCohort StudiesBiomarkersSurvival RateCytokines
Funding
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Fundação Oswaldo Cruz
Citations
739
FWCI
21.36
field-weighted impact
References
46
Percentile
100%
vs. same field & year
Citations per year
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