review Open AccessTop 1% cited
A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis
Diabetologia · 2001 · Vol. 44(12) · pp. 2115–2133
Décio L. Eizirik✉(Vrije Universiteit Brussel)Thomas Mandrup‐Poulsen(Steno Diabetes Center)
Adipokines, Inflammation, and Metabolic DiseasesDiabetes and associated disordersPancreatic function and diabetesCell biologySignal transductionBiologyFas ligandProgrammed cell deathT cellCytokineApoptosisImmune systemImmunology
MeSH terms
AnimalsDiabetes Mellitus, Type 1Immune SystemIslets of LangerhansSignal TransductionApoptosis
Funding
- Fonds Wetenschappelijk Onderzoek
- Novo Nordisk
- Diabetesforeningen
Citations
883
FWCI
20.40
field-weighted impact
References
120
Percentile
100%
vs. same field & year
Citations per year
Cited by
Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes
Diabetes · 2005 · 1,475 citations
The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus
Endocrine Reviews · 2007 · 1,158 citations
Oxidative stress: the vulnerable β-cell
Biochemical Society Transactions · 2008 · 516 citations
Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
Frontiers in Physiology · 2020 · 1,048 citations
Oxidative stress and beta-cell dysfunction
Pflügers Archiv - European Journal of Physiology · 2010 · 311 citations
Roles of CHOP/GADD153 in endoplasmic reticulum stress
Cell Death and Differentiation · 2003 · 2,809 citations
References
High density synthetic oligonucleotide arrays
Nature Genetics · 1999 · 2,217 citations
Morphologic and biochemical hallmarks of apoptosis
Cardiovascular Research · 2000 · 1,452 citations
NF-κB: a key role in inflammatory diseases
Journal of Clinical Investigation · 2001 · 3,853 citations
When Two Strands Are Better Than One: The Mediators and Modulators of the Cellular Responses to Double-Stranded RNA
Virology · 1996 · 576 citations
HOW CELLS RESPOND TO INTERFERONS
Annual Review of Biochemistry · 1998 · 3,942 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.