reviewTop 1% cited
5-Aminolevulinic acid-based photodynamic therapy
Cancer · 1997 · Vol. 79(12) · pp. 2282–2308
Qian Peng✉(University of Oslo)Trond Warloe(University of Oslo)Kristian Berg(University of Oslo)Johan Moan(Norwegian Cancer Society)Magne Kongshaug(University of Oslo)Karl-Erik Giercksky(University of Oslo)Jahn M. Nesland(Oslo University Hospital)
Abstract
Promising results of ALA-based clinical PDT and diagnosis have been obtained. The modality has advantages over conventional treatments. However, some improvements need to be made, such as optimization of parameters of ALA-based PDT and diagnosis; increased tumor selectivity of ALA-derived PpIX; better understanding of light distribution in tissue: improvement of light dosimetry procedure; and development of simpler, cheaper, and more efficient light delivery systems.
Photodynamic Therapy Research StudiesNanoplatforms for cancer theranosticsNonmelanoma Skin Cancer StudiesPhotodynamic therapyMedicinePhotosensitizerProtoporphyrin IXSkin cancerProdrugDermatologyClinical trialProtoporphyrinCancer
MeSH terms
Aminolevulinic AcidForecastingHemeHumansNeoplasmsPhotochemotherapyProtoporphyrinsResearchSkin DiseasesSkin Neoplasms
Citations
974
FWCI
25.71
field-weighted impact
References
213
Percentile
100%
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References
Porphyrin localization and treatment of tumors
British Journal of Cancer · 1985 · 636 citations
Photodynamic therapy of non-melanoma malignant tumours of the skin using topical δ-amino levulinic acid sensitization and laser irradiation
British Journal of Dermatology · 1994 · 427 citations
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