review Open AccessTop 1% cited
The statistical-thermodynamic basis for computation of binding affinities: a critical review
Biophysical Journal · 1997 · Vol. 72(3) · pp. 1047–1069
Michael K. Gilson✉(National Institute of Standards and Technology)James A. Given(National Institute of Standards and Technology)Bruce L. Bush(National Institute of Standards and Technology)J. Andrew McCammon(National Institute of Standards and Technology)
Spectroscopy and Quantum Chemical StudiesFree Radicals and Antioxidantsthermodynamics and calorimetric analysesAffinitiesBinding affinitiesChemistryStatistical physicsEntropy (arrow of time)Statistical mechanicsBinding energyComputationThermodynamicsFormalism (music)
MeSH terms
Binding SitesLigandsModels, ChemicalModels, StructuralPotentiometryProtein ConformationProteinsSolutionsSolventsThermodynamicsModels, StatisticalEntropy
Citations
1,252
FWCI
20.96
field-weighted impact
References
45
Percentile
100%
vs. same field & year
Citations per year
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References
Proteins under pressure
European Journal of Biochemistry · 1994 · 693 citations
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