article Open AccessTop 10% cited

Curcumin is a potent DNA hypomethylation agent

Bioorganic & Medicinal Chemistry Letters · 2008 · Vol. 19(3) · pp. 706–709

Zhongfa Liu✉(The Ohio State University)Zhiliang Xie(The Ohio State University)W.P. Jones(The Ohio State University)Ryan E. Pavlovicz(The Ohio State University)Shujun Liu(The Ohio State University)Jianhua Yu(The Ohio State University)Pui‐Kai Li(The Ohio State University)Jiayuh Lin(Nationwide Children's Hospital)James R. Fuchs(The Ohio State University)Guido Marcucci(The Ohio State University)Chenglong Li(The Ohio State University)Kenneth K. Chan(The Ohio State University)

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Epigenetics and DNA Methylation RNA modifications and cancer Advanced biosensing and bioanalysis techniquesCurcuminChemistryDNMT1IC50BiochemistryDocking (animal)In vitroInhibitory postsynaptic potentialDNACell culture

MeSH terms

DNA (Cytosine-5-)-Methyltransferase 1CatalysisCurcuminCytosineDNA (Cytosine-5-)-MethyltransferasesDose-Response Relationship, DrugHumansLeukemiaModels, ChemicalMolecular ConformationDrug DesignDNA MethylationInhibitory Concentration 50Catalytic DomainCell Line, Tumor

Funding

National Institutes of Health

Citations

321

FWCI

4.28

field-weighted impact

References

Percentile

95%

vs. same field & year

Citations per year

Cited by

DNA Methyltransferases: A Novel Target for Prevention and Therapy

Frontiers in Oncology · 2014 · 468 citations

References

NMR Study of the Solution Structure of Curcumin

Journal of Natural Products · 2007 · 367 citations

Decitabine improves patient outcomes in myelodysplastic syndromes

Cancer · 2006 · 1,506 citations

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