articleTop 1% cited
The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome
Journal of the Neurological Sciences · 1989 · Vol. 89(2-3) · pp. 169–179
David M. A. Mann✉(University of Manchester)Margaret M. Esiri(University of Oxford)
Alzheimer's disease research and treatmentsDown syndrome and intellectual disability researchDementia and Cognitive Impairment ResearchSenile plaquesPathologyEntorhinal cortexTangleSilver stainCortex (anatomy)Neurofibrillary tangleAlzheimer's diseaseStainingPopulation
MeSH terms
AdultAge FactorsBrainChildDown SyndromeFemaleHumansMaleMiddle AgedNeurofibrils
Citations
473
FWCI
13.07
field-weighted impact
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20
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99%
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Citations per year
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Neurobiology of Aging · 1991 · 826 citations
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References
Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome
Annals of Neurology · 1985 · 1,160 citations
Amyloid plaque core protein in Alzheimer disease and Down syndrome.
Proceedings of the National Academy of Sciences · 1985 · 4,412 citations
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