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Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis

British journal of surgery · 2002 · Vol. 89(3) · pp. 298–302
Anton ButerC W ImrieC R CarterSusan EvansC. McKay

Abstract

Early organ dysfunction in acute pancreatitis usually resolves and in itself has no significant influence on mortality. In contrast, worsening organ dysfunction was associated with death in more than half of the patients (11 of 20); it is this group of patients who should be classified as having severe acute pancreatitis.

Pancreatitis Pathology and TreatmentDiabetes and associated disordersLiver Disease Diagnosis and TreatmentMedicineOrgan dysfunctionAcute pancreatitisOutcome (game theory)Intensive care medicinePancreatitisMultiple organ dysfunction syndromeInternal medicineSepsis

MeSH terms

Acute DiseaseAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedMultiple Organ FailurePancreatitisProspective StudiesTime FactorsSurvival AnalysisSystemic Inflammatory Response Syndrome

Funding

  • University of Glasgow
Citations
552
FWCI
14.26
field-weighted impact
References
32
Percentile
99%
vs. same field & year
Citations per year
References
A Clinically Based Classification System for Acute Pancreatitis
Archives of Surgery · 1993 · 2,756 citations
Multiple-Organ Failure
Archives of Surgery · 1985 · 1,303 citations
Multiple Organ Failure in Polytrauma Patients
The Journal of Trauma: Injury, Infection, and Critical Care · 1983 · 493 citations
Death due to acute pancreatitis
Digestive Diseases and Sciences · 1985 · 471 citations
APACHE II-A Severity of Disease Classification System
Critical Care Medicine · 1986 · 13,403 citations
Multiple Organ Dysfunction Score
Critical Care Medicine · 1995 · 2,523 citations
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