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Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction

New England Journal of Medicine · 2002 · Vol. 346(12) · pp. 877–883

Arthur J. Moss✉(University of Rochester Medical Center)Wojciech ZarębaWilliam J. HallHelmut Klein(University Hospital Magdeburg)David J. WilberDavid S. Cannom(Good Samaritan Hospital)James P. DaubertSteven L. HigginsMary W. BrownMark Andrews

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Abstract

In patients with a prior myocardial infarction and advanced left ventricular dysfunction, prophylactic implantation of a defibrillator improves survival and should be considered as a recommended therapy.

Cardiac pacing and defibrillation studies Cardiac electrophysiology and arrhythmias Cardiovascular Function and Risk FactorsMedicineEjection fractionCardiologyMyocardial infarctionInternal medicineVentricular functionRandomized controlled trialImplantable cardioverter-defibrillatorHeart failure

MeSH terms

Adrenergic beta-AntagonistsAgedAmiodaroneAngiotensin-Converting Enzyme InhibitorsAnti-Arrhythmia AgentsHypolipidemic AgentsArrhythmias, CardiacCombined Modality TherapyFemaleHumansMaleMiddle AgedMyocardial InfarctionStroke VolumeProportional Hazards Models

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