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Microfluidic flow focusing: Drop size and scaling in pressure <b><i>versus</i></b> flow‐rate‐driven pumping

Electrophoresis · 2005 · Vol. 26(19) · pp. 3716–3724
Thomas WardMagalie FaivreManouk AbkarianHoward A. Stone

Abstract

We experimentally study the production of micrometer-sized droplets using microfluidic technology and a flow-focusing geometry. Two distinct methods of flow control are compared: (i) control of the flow rates of the two phases and (ii) control of the inlet pressures of the two phases. In each type of experiment, the drop size l, velocity U and production frequency f are measured and compared as either functions of the flow-rate ratio or the inlet pressure ratio. The minimum drop size in each experiment is on the order of the flow focusing contraction width a. The variation in drop size as the flow control parameters are varied is significantly different between the flow-rate and inlet pressure controlled experiments.

Innovative Microfluidic and Catalytic Techniques InnovationMicrofluidic and Capillary Electrophoresis ApplicationsMicrofluidic and Bio-sensing TechnologiesPressure dropVolumetric flow rateFlow focusingMechanicsDrop (telecommunication)InletFlow coefficientMicrofluidicsMaterials scienceFlow control (data)

MeSH terms

PressureMicrofluidicsMicrofluidic Analytical Techniques
Citations
349
FWCI
12.85
field-weighted impact
References
21
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References
Formation of dispersions using “flow focusing” in microchannels
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Electrophoresis · 2000 · 3,180 citations
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