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The Relative Impact of Anxiety, Depression, and Clinical Seizure Features on Health‐related Quality of Life in Epilepsy

Epilepsia · 2004 · Vol. 45(5) · pp. 544–550
Erica K. JohnsonJana E. JonesMichael SeidenbergBruce P. Hermann

Abstract

Interictal anxiety and depression exert independent adverse effects on HRQOL. In addition, frequent, severe, and chronic seizures reduce HRQOL, but appear less powerful predictors of HRQOL than interictal psychiatric symptoms. Recognition and treatment of comorbid depression and anxiety is an important consideration in improving quality of life in epilepsy.

Epilepsy research and treatmentPharmacological Effects and Toxicity StudiesNeuroscience and Neuropharmacology ResearchEpilepsyAnxietyComorbidityDepression (economics)IctalQuality of life (healthcare)PsychiatryPsychologyMedicineClinical psychology

MeSH terms

AdultAnxiety DisordersChronic DiseaseDepressive DisorderEpilepsy, Temporal LobeFemaleHealth StatusHumansMaleModels, PsychologicalPersonality InventoryQuality of LifeSurveys and QuestionnairesRegression AnalysisSeverity of Illness Index
Citations
517
FWCI
10.30
field-weighted impact
References
41
Percentile
99%
vs. same field & year
Citations per year
References
An Inventory for Measuring Depression
Archives of General Psychiatry · 1961 · 37,929 citations
The Epidemiology of Major Depressive Disorder
JAMA · 2003 · 7,949 citations
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