articleTop 10% cited

Systemic chemerin is related to inflammation rather than obesity in type 2 diabetes

Clinical Endocrinology · 2009 · Vol. 72(3) · pp. 342–348

Johanna Weigert✉(University Hospital Regensburg)Markus NeumeierJosef WanningerMichael FilarskySabrina BauerReiner WiestStefan FarkasMarcus N. SchererAndréas SchäfflerCharalampos Aslanidis(University Hospital Regensburg)Jürgen SchölmerichChrista Buechler

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Abstract

Visceral fat is not a major site of chemerin release, and elevated systemic levels of chemerin in obesity and T2D seem to be associated with inflammation rather than body mass index.

Adipokines, Inflammation, and Metabolic Diseases Adipose Tissue and Metabolism Lower Extremity Biomechanics and PathologiesChemerinInternal medicineAdipokineEndocrinologyMedicineType 2 diabetesInflammationCirrhosisBody mass indexDiabetes mellitus

MeSH terms

AdultAgedAged, 80 and overDiabetes Mellitus, Type 2FemaleHepatic VeinsHumansInflammationMaleMiddle AgedObesityPortal VeinChemokinesIntercellular Signaling Peptides and Proteins

Citations

289

FWCI

10.01

field-weighted impact

References

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99%

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References

Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?