article Open AccessTop 1% cited
Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation
Molecular Cell · 2000 · Vol. 6(6) · pp. 1365–1375
Peter A. Kavsak(Mount Sinai Hospital)Richele K. Rasmussen(Mount Sinai Hospital)Carrie G. Causing(Mount Sinai Hospital)Shirin Bonni(Mount Sinai Hospital)Haitao Zhu(State University of New York)Gerald H. Thomsen(State University of New York)Jeffrey L. Wrana✉(Mount Sinai Hospital)
TGF-β signaling in diseasesUbiquitin and proteasome pathwaysCancer-related gene regulationUbiquitin ligaseUbiquitinBiologyReceptorUbiquitin-Protein LigasesSignal transducing adaptor proteinCell biologyProteolysisTransforming growth factorSignal transduction
MeSH terms
AnimalsCell LineCysteine EndopeptidasesDNA-Binding ProteinsGene Expression RegulationInterferon-gammaLigasesLysosomesModels, BiologicalMolecular Sequence DataMultienzyme ComplexesMutationNuclear ProteinsProtein BindingRecombinant Fusion Proteins
Citations
1,326
FWCI
17.33
field-weighted impact
References
37
Percentile
100%
vs. same field & year
Citations per year
Cited by
Smad regulation in TGF-β signal transduction
Journal of Cell Science · 2001 · 924 citations
TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis
Journal of Histochemistry & Cytochemistry · 2016 · 711 citations
TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES
Annual Review of Immunology · 2005 · 2,164 citations
TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019
Cells · 2019 · 752 citations
Role of Smads in TGFβ signaling
Cell and Tissue Research · 2011 · 322 citations
TGF-? receptor function in the endothelium
Cardiovascular Research · 2004 · 508 citations
TGF‐β signaling: A tale of two responses
Journal of Cellular Biochemistry · 2007 · 372 citations
TGFβ signalling in context
Nature Reviews Molecular Cell Biology · 2012 · 3,088 citations
References
THE UBIQUITIN SYSTEM
Annual Review of Biochemistry · 1998 · 8,726 citations
Controlling TGF-β signaling
Genes & Development · 2000 · 1,563 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.