reviewTop 1% cited
Molecular mechanisms of drug addiction
Neuropharmacology · 2004 · Vol. 47 · pp. 24–32
Eric J. Nestler✉(The University of Texas Southwestern Medical Center)
Neurotransmitter Receptor Influence on BehaviorReceptor Mechanisms and SignalingAdipose Tissue and MetabolismNucleus accumbensAddictionCREBNeuroscienceMechanism (biology)DrugBrain stimulation rewardTranscription factorDrugs of abuseSensitization
MeSH terms
AnimalsHumansProto-Oncogene Proteins c-fosCyclic AMP Response Element-Binding ProteinSubstance-Related Disorders
Funding
- National Institute on Drug Abuse
Citations
1,099
FWCI
19.70
field-weighted impact
References
126
Percentile
100%
vs. same field & year
Citations per year
Cited by
Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase
American Journal of Physiology-Renal Physiology · 2000 · 393 citations
Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction
Philosophical Transactions of the Royal Society B Biological Sciences · 2008 · 957 citations
Cellular mechanisms of nicotine addiction
Pharmacology Biochemistry and Behavior · 2001 · 406 citations
The Development and Maintenance of Drug Addiction
Neuropsychopharmacology · 2013 · 553 citations
The role of stress in drug self-administration
Trends in Pharmacological Sciences · 1998 · 665 citations
Temperament and developmental psychopathology
Journal of Child Psychology and Psychiatry · 2006 · 960 citations
The role of dopamine in drug abuse viewed from the perspective of its role in motivation
Drug and Alcohol Dependence · 1995 · 624 citations
Drug dependence: stress and dysregulation of brain reward pathways
Drug and Alcohol Dependence · 1998 · 705 citations
References
Molecular basis of long-term plasticity underlying addiction
Nature reviews. Neuroscience · 2001 · 1,855 citations
Neurobiology of Depression
Neuron · 2002 · 3,159 citations
Transcriptional regulation by the phosphorylation-dependent factor CREB
Nature Reviews Molecular Cell Biology · 2001 · 2,568 citations
The regulation and function of c-fos and other immediate early genes in the nervous system
Neuron · 1990 · 2,439 citations
A psychomotor stimulant theory of addiction.
Psychological Review · 1987 · 2,703 citations
CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals
Annual Review of Biochemistry · 1999 · 2,134 citations
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
Proceedings of the National Academy of Sciences · 1988 · 4,701 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
