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Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects.
British Journal of Clinical Pharmacology · 1983 · Vol. 15(2) · pp. 161–165
MJ Cushley✉(Southampton General Hospital)AE Tattersfield(Southampton General Hospital)ST Holgate
Abstract
1 The airway response to the inhaled nucleosides, adenosine (6.7 x 10-4-6.7 mg/ml) and guanosine (7.3 x 10-4-1.4 mg/ml) was studied in normal and asthmatic subjects. Airway response, measured in the body plethysmograph, was expressed as percentage change in specific airway conductance (sGaw) from baseline.
Respiratory and Cough-Related ResearchPharmaceutical studies and practicesGastroesophageal reflux and treatmentsAdenosineGuanosineMedicineAirway resistanceAirwayAsthmaTheophyllinePharmacologyInhalationAnesthesia
Citations
371
FWCI
16.36
field-weighted impact
References
28
Percentile
100%
vs. same field & year
Citations per year
References
Adenosine 3‘,5‘-Phosphate in Biological Materials
Journal of Biological Chemistry · 1962 · 2,087 citations
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