reviewTop 1% cited

Biological activities of laminin

Journal of Cellular Biochemistry · 1985 · Vol. 27(4) · pp. 317–325

Hynda K. Kleinman✉(National Institutes of Health)Frances B. Cannon(National Institutes of Health)Gordon W. Laurie(National Institutes of Health)John R. Hassell(National Institute of Dental and Craniofacial Research)Monique Aumailley(National Institute of Dental and Craniofacial Research)Victor P. Terranova(National Institutes of Health)George R. Martin(National Institutes of Health)M. Dubois-Dalcq(National Institute of Neurological Disorders and Stroke)

View via DOI Publisher page

Abstract

Laminin is a multifunctional protein with diverse biological activities. Like fibronectin, it can influence cell adhesion, growth, morphology, differentiation, migration, and agglutination as well as the assembly of the extracellular matrix. Laminin primarily affects cells of epithelial origin, and the response varies depending on the cell. Because most differentiated cells are difficult to maintain in culture, laminin may be an important supplement in studies on cell differentiation in vitro.

Cell Adhesion Molecules Research Silk-based biomaterials and applications Protease and Inhibitor MechanismsLamininFibronectinExtracellular matrixCell biologyCell adhesionAdhesionIn vitroCellular differentiationCellBiology

MeSH terms

AnimalsBasement MembraneBinding SitesCell AdhesionCell DifferentiationCell DivisionCell MovementCellsCells, CulturedChemistryCollagenExtracellular MatrixHemagglutinationHeparinHeparitin Sulfate

Citations

466

FWCI

12.88

field-weighted impact

References

Percentile

99%

vs. same field & year

Citations per year

Cited by

Structure and biological activity of basement membrane proteins