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The basics of thiols and cysteines in redox biology and chemistry

Free Radical Biology and Medicine · 2014 · Vol. 80 · pp. 148–157
Leslie B. Poole
Redox biology and oxidative stressSulfur Compounds in BiologyGenomics, phytochemicals, and oxidative stressCysteineChemistryRedoxResidue (chemistry)ThiolDisulfide bondAmino acidNucleophileBiochemistryCysteine metabolism

MeSH terms

AnimalsCysteineDisulfidesElectronsFree RadicalsGlutathioneHumansKineticsOxidation-ReductionOxidoreductasesSulfhydryl CompoundsThermodynamicsSignal TransductionBiocatalysis

Funding

  • National Institutes of Health
Citations
971
FWCI
13.95
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References
143
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99%
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Thiol redox control via thioredoxin and glutaredoxin systems
Biochemical Society Transactions · 2005 · 377 citations
Thiol chemistry and specificity in redox signaling
Free Radical Biology and Medicine · 2008 · 1,226 citations
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism
Biochimica et Biophysica Acta (BBA) - General Subjects · 2008 · 409 citations
Nitric Oxide and Peroxynitrite in Health and Disease
Physiological Reviews · 2007 · 6,199 citations
Hydroperoxide metabolism in mammalian organs.
Physiological Reviews · 1979 · 5,812 citations
Thiol redox control via thioredoxin and glutaredoxin systems
Biochemical Society Transactions · 2005 · 345 citations
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