article Open AccessTop 1% cited
3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs
Advanced Materials · 2014 · Vol. 26(19) · pp. 3124–3130
David B. Kolesky(Harvard University)Ryan L. Truby(Harvard University)A. Sydney Gladman(Harvard University)Travis A. Busbee(Harvard University)Kimberly A. Homan(Harvard University)Jennifer A. Lewis✉(Harvard University)
Abstract
A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new -avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.
3D Printing in Biomedical ResearchInnovative Microfluidic and Catalytic Techniques InnovationPluripotent Stem Cells ResearchComputer scienceService (business)NanotechnologyTissue engineeringExtracellular matrixMaterials scienceDrug deliveryData scienceWorld Wide WebBiomedical engineering
MeSH terms
Extracellular MatrixHumansPolyethylene GlycolsPropylene GlycolsPoloxamerTissue EngineeringHuman Umbilical Vein Endothelial CellsBioprinting
Funding
- Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University
Citations
2,036
FWCI
96.91
field-weighted impact
References
36
Percentile
100%
vs. same field & year
Citations per year
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References
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The Journal of Physiology · 1919 · 1,425 citations
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Nature Materials · 2005 · 3,868 citations
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Biomaterials · 2000 · 4,919 citations
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