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Evidence of a Substantial Genetic Basis for Risk of Adult Periodontitis

Journal of Periodontology · 2000 · Vol. 71(11) · pp. 1699–1707

Bryan S. Michalowicz✉(University of Minnesota)Scott R. DiehlJohn C. Gunsolley(Virginia Commonwealth University)Brandon S. Sparks(Virginia Commonwealth University)Carol N. Brooks(Virginia Commonwealth University)Thomas E. Koertge(Virginia Commonwealth University)Joseph V. Califano(Virginia Commonwealth University)J. A. Burmeister(Virginia Commonwealth University)Harvey A. Schenkein(Virginia Commonwealth University)

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Abstract

These results confirm previous studies and indicate that approximately half of the variance in disease in the population is attributed to genetic variance. The basis for the heritability of periodontitis appears to be biological and not behavioral in nature.

Oral microbiology and periodontitis research Oral Health Pathology and Treatment Dental Health and Care UtilizationHeritabilityGingivitisPeriodontitisGenetic correlationTwin studyPopulationMedicineDemographyBiologyDentistry

MeSH terms

AdultAgedAged, 80 and overAnalysis of VarianceDental CareDental Plaque IndexFemaleHumansMaleMiddle AgedPeriodontal IndexPeriodontitisRisk FactorsSmokingGenetic Variation