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Behavioural and pharmacological characterisation of the elevated “zero-maze” as an animal model of anxiety

Psychopharmacology · 1994 · Vol. 116(1) · pp. 56–64
Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology ResearchMemory and Neural MechanismsChlordiazepoxideAnxiogenicElevated plus mazeDiazepamPharmacologyFlumazenilAnxiolyticAgonistBenzodiazepinePsychology

MeSH terms

AnimalsAnxietyBehavior, AnimalChlordiazepoxideDiazepamDisease Models, AnimalDose-Response Relationship, DrugMalePiperazinesPostureAnti-Anxiety AgentsRats, Sprague-DawleyOndansetronSerotonin Receptor Agonists8-Hydroxy-2-(di-n-propylamino)tetralin
Citations
739
FWCI
3.28
field-weighted impact
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55
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94%
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Cited by
A review of the validity and variability of the Elevated Plus-Maze as an animal model of anxiety
Pharmacology Biochemistry and Behavior · 1996 · 1,162 citations
Anxiety, defence and the elevated plus-maze
Neuroscience & Biobehavioral Reviews · 1997 · 984 citations
Use of the elevated plus maze in the search for novel anxiolytic agents
Trends in Pharmacological Sciences · 1995 · 561 citations
References
Thigmotaxis as a test for anxiolytic activity in rats
Pharmacology Biochemistry and Behavior · 1988 · 668 citations
Anxiogenic stimuli in the elevated plus-maze
Pharmacology Biochemistry and Behavior · 1993 · 619 citations
The use of a plus-maze to measure anxiety in the mouse
Psychopharmacology · 1987 · 2,598 citations
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