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Preventing Renal Failure in Patients with Rhabdomyolysis: Do Bicarbonate and Mannitol Make a Difference?
The Journal of Trauma: Injury, Infection, and Critical Care · 2004 · Vol. 56(6) · pp. 1191–1196
Carlos Brown✉(State Street (United States))Peter Rhee(State Street (United States))Linda S. Chan(State Street (United States))Kelly Evans(State Street (United States))Δημήτριος Δημητριάδης(State Street (United States))George C. Velmahos(State Street (United States))
Abstract
Abnormal CK levels are common among critically injured patients, and a CK level greater than 5,000 U/L is associated with RF. BIC/MAN does not prevent RF, dialysis, or mortality in patients with creatine kinase levels greater than 5,000 U/L. The standard of administering BIC/MAN to patients with post-traumatic rhabdomyolysis should be reevaluated.
Muscle and Compartmental DisordersTrauma, Hemostasis, Coagulopathy, ResuscitationElectrolyte and hormonal disordersMedicineRhabdomyolysisCreatine kinaseDialysisIntensive care unitCreatinineInternal medicineCreatine
MeSH terms
Creatine KinaseDiuretics, OsmoticDrug Therapy, CombinationFemaleHumansMaleMannitolMiddle AgedRhabdomyolysisRisk FactorsLogistic ModelsOdds RatioSodium BicarbonateAcute Kidney Injury
Citations
397
FWCI
12.03
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References
Rhabdomyolysis
Journal of the American Society of Nephrology · 2000 · 657 citations
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