article
Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination
Journal of Theoretical Biology · 1979 · Vol. 81(4) · pp. 645–670
Alan S. Perelson✉(Brown University)George Oster(University of California, Berkeley)
T-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies ResearchImmune Response and InflammationRepertoireImmune systemAntibodyAntibody RepertoireAntigenBiologyProbabilistic logicSelection (genetic algorithm)Computational biologyImmunology
MeSH terms
AnimalsAntibody DiversityAntibody SpecificityAntigen-Antibody ReactionsEpitopesBinding Sites, AntibodyClone CellsBiological EvolutionGenes, MHC Class IIGuinea PigsLymphocytesModels, BiologicalProbabilityMice
Citations
647
FWCI
0.40
field-weighted impact
References
43
Percentile
56%
vs. same field & year
Citations per year
Cited by
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References
Statistical Theory of Reliability and Life Testing-Probability Models
Technometrics · 1977 · 3,710 citations
Mathematical Theory of Reliability
Econometrica · 1966 · 2,719 citations
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