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PLEK: a tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme

BMC Bioinformatics · 2014 · Vol. 15(1) · pp. 311–311
Aimin LiJunying ZhangZhongyin Zhou

Abstract

PLEK is an efficient alignment-free computational tool to distinguish lncRNAs from mRNAs in RNA-seq transcriptomes of species lacking reference genomes. PLEK is especially suitable for PacBio or 454 sequencing data and large-scale transcriptome data. Its open-source software can be freely downloaded from https://sourceforge.net/projects/plek/files/.

Cancer-related molecular mechanisms researchGenomics and Phylogenetic StudiesRNA modifications and cancerComputational biologyRefSeqGene predictionTranscriptomeComputer scienceBiologyGeneGeneticsGenomeGene expression

MeSH terms

AlgorithmsAnimalsHumansProteinsRNA, MessengerSoftwareSequence Analysis, RNAComputational BiologyGene Expression ProfilingDatabases, GeneticMiceMolecular Sequence AnnotationSupport Vector MachineRNA, Long Noncoding

Funding

  • National Natural Science Foundation of China
  • Specialized Research Fund for the Doctoral Program of Higher Education of China
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PLEK: a tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme · Scinovex