articleTop 1% cited
Clinical development success rates for investigational drugs
Nature Biotechnology · 2014 · Vol. 32(1) · pp. 40–51
Michael Hay✉David W. Thomas(Biotechnology Innovation Organization)John L. CraigheadCelia Economides(Biotechnology Innovation Organization)Jesse Rosenthal
Pharmaceutical Economics and PolicyBiotechnology and Related FieldsHealth Systems, Economic Evaluations, Quality of LifeInvestigational DrugsDrug developmentDrug approvalMedicineIntensive care medicinePharmacologyComputational biologyClinical trialInternal medicineBiology
MeSH terms
HumansUnited StatesUnited States Food and Drug AdministrationDrugs, InvestigationalDrug ApprovalBiomedical Research
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References
Can the pharmaceutical industry reduce attrition rates?
Nature Reviews Drug Discovery · 2004 · 4,081 citations
Risks in new drug development: Approval success rates for investigational drugs
Clinical Pharmacology & Therapeutics · 2001 · 455 citations
Trends in Risks Associated With New Drug Development: Success Rates for Investigational Drugs
Clinical Pharmacology & Therapeutics · 2010 · 839 citations
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