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Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

Developmental Cell · 2013 · Vol. 24(4) · pp. 384–399
Florian WilflingHuajin WangJoel T. HaasNatalie KrahmerTravis J. GouldAki UchidaJi‐Xin ChengMorven GrahamRomain ChristianoFlorian FröhlichXinran LiuKimberly K. BuhmanRosalind ColemanJoerg BewersdorfRobert V. FareseTobias C. Walther
Lipid metabolism and biosynthesisPhotosynthetic Processes and MechanismsAdipose Tissue and MetabolismLipid dropletBiologyEndoplasmic reticulumBiochemistryLipid metabolismPopulationEnzymeCell biology

MeSH terms

AnimalsCells, CulturedEmbryo, MammalianEndoplasmic ReticulumFibroblastsGlycerol-3-Phosphate O-AcyltransferaseLipidsMice, TransgenicPhospholipidsTriglyceridesImmunoblottingMice, KnockoutImmunoprecipitationLipid MetabolismDiacylglycerol O-Acyltransferase

Funding

  • American Historical Association
  • Gladstone Institutes
  • National Institute of General Medical Sciences
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Cited by
Dynamics and functions of lipid droplets
Nature Reviews Molecular Cell Biology · 2018 · 2,623 citations
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Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets · Scinovex