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Use of the Barthel Index and Modified Rankin Scale in Acute Stroke Trials

Stroke · 1999 · Vol. 30(8) · pp. 1538–1541

Geert Sulter✉(Martini Ziekenhuis)Christel Steen(Martini Ziekenhuis)Jacques De Keyser(Martini Ziekenhuis)

Abstract

Among the efficacy trials in acute stroke, we found remarkable differences in the choice of primary end points and in the definition of favorable outcome on both the BI and MRS. This lack of consensus strongly hinders the design, interpretation, and comparison of acute stroke trials. In general, it may be easier to define poor outcome instead of favorable outcome. Poor outcome could be defined if any of the following end points are reached: death, institutionalization due to stroke, MRS >3, or BI <60.

Acute Ischemic Stroke Management Stroke Rehabilitation and Recovery Venous Thromboembolism Diagnosis and ManagementMedicineModified Rankin ScaleBarthel indexStroke (engine)Clinical trialAcute strokePhysical therapyRandomized controlled trialOutcome (game theory)Activities of daily living

MeSH terms

Acute DiseaseBrain IschemiaDisability EvaluationFibrinolytic AgentsHumansRetrospective StudiesSeverity of Illness IndexThrombolytic TherapyRandomized Controlled Trials as TopicTreatment OutcomeClinical Trials, Phase III as Topic