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Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat

Archives of Biochemistry and Biophysics · 1985 · Vol. 238(1) · pp. 43–48
Ronald A. LubetRichard T. MayerJohn W. CameronRaymond W. NimsM.D. BurkeThomas WolffF. Peter Guengerich
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance MechanismsGlutathione Transferases and PolymorphismsPhenobarbitalMicrosomeChemistryCytochromeMetyraponeCytochrome P450MicrosomaMethylcholanthreneCarcinogenGlutathione

MeSH terms

Aminopyrine N-DemethylaseAnimalsAroclorsCytochrome P-450 Enzyme SystemDealkylationEnzyme InductionMaleMethylcholanthreneMicrosomes, LiverOxazinesOxidoreductasesOxidoreductases, N-DemethylatingPhenobarbitalSubstrate SpecificityCytochrome P-450 CYP2B1
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654
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13.78
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Cited by
In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin
Toxicology and Applied Pharmacology · 1992 · 364 citations
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Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat · Scinovex