reviewTop 1% cited
The effect of treatment with omalizumab, an anti‐IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma
Allergy · 2004 · Vol. 60(3) · pp. 302–308
Jean Bousquet✉(Hôpital Arnaud de Villeneuve)Pedro Cabrera(Hospital Universitario de Gran Canaria Doctor Negrín)Neville Berkman(Hadassah Medical Center)Roland Buhl(Johannes Gutenberg University Mainz)Stephen T. Holgate(Southampton General Hospital)Sally E. Wenzel(University of Colorado Denver)Helen Fox(Novartis (United Kingdom))S. Hedgecock(Novartis (United Kingdom))Martin Blogg(Novartis (United Kingdom))Giovanni Della Cioppa(Novartis (United Kingdom))
Abstract
These results suggest that omalizumab may fulfil an important need in patients with severe persistent asthma, many of whom are not adequately controlled on current therapy.
Asthma and respiratory diseasesRespiratory and Cough-Related ResearchAllergic Rhinitis and SensitizationOmalizumabMedicineAsthmaExacerbationImmunoglobulin EPoisson regressionEmergency departmentPlaceboInternal medicineRate ratio
MeSH terms
OmalizumabAntibodies, Anti-IdiotypicAntibodies, MonoclonalAsthmaEmergency Medical ServicesHumansImmunoglobulin ESeverity of Illness IndexRandomized Controlled Trials as TopicAnti-Asthmatic AgentsAntibodies, Monoclonal, Humanized
Citations
399
FWCI
13.07
field-weighted impact
References
25
Percentile
99%
vs. same field & year
Citations per year
Cited by
British Guideline on the Management of Asthma
Thorax · 2008 · 2,029 citations
References
The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics
European Respiratory Journal · 2001 · 826 citations
Efficacy and tolerability of anti‐immunoglobulin E therapy with omalizumab in patients with concomitant allergic asthma and persistent allergic rhinitis: SOLAR
Allergy · 2004 · 404 citations
Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
Journal of Allergy and Clinical Immunology · 2001 · 1,287 citations
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