articleTop 1% cited
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
The Lancet Neurology · 2013 · Vol. 12(2) · pp. 207–216
Clifford R. Jack✉(Mayo Clinic)David S. Knopman(Mayo Clinic in Arizona)William J. Jagust(University of California, Berkeley)Ronald C. Petersen(Mayo Clinic in Arizona)Michael W. Weiner(University of California, San Francisco)Paul Aisen(University of California, San Diego)Leslie M. Shaw(Institute on Aging)Prashanthi VemuriHeather J. Wiste(Mayo Clinic in Florida)Stephen D. Weigand(Mayo Clinic in Florida)Timothy G. Lesnick(Mayo Clinic in Florida)V. Shane Pankratz(Mayo Clinic in Florida)Michael Donohue(University of California, San Diego)John Q. Trojanowski(University of Pennsylvania)
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment ResearchFunctional Brain Connectivity StudiesTauopathyNeuroscienceDiseaseMedicineBiomarkerPathophysiologyPsychologyPathologyNeurodegenerationBiology
MeSH terms
Alzheimer DiseaseCognition DisordersHumansModels, BiologicalBiomarkersAmyloid beta-Peptidestau ProteinsNonlinear Dynamics
Funding
- Mayo Clinic
- National Institutes of Health
Citations
4,351
FWCI
156.11
field-weighted impact
References
123
Percentile
100%
vs. same field & year
Citations per year
Cited by
Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease
Science Translational Medicine · 2016 · 732 citations
Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association
Hypertension · 2016 · 710 citations
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts
The Lancet Neurology · 2020 · 1,309 citations
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study
The Lancet Neurology · 2013 · 2,242 citations
The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques
Cell Reports · 2019 · 950 citations
Tau PET imaging in neurodegenerative tauopathies—still a challenge
Molecular Psychiatry · 2019 · 614 citations
Current state of Alzheimer’s fluid biomarkers
Acta Neuropathologica · 2018 · 514 citations
Impact of multiple pathologies on the threshold for clinically overt dementia
Acta Neuropathologica · 2017 · 689 citations
References
Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories
Neurobiology of Aging · 1997 · 1,666 citations
Tangles and plaques in nondemented aging and ?preclinical? Alzheimer's disease
Annals of Neurology · 1999 · 1,682 citations
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ <sub>42</sub> in humans
Annals of Neurology · 2005 · 1,247 citations
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
Annals of Neurology · 2009 · 2,070 citations
Cerebrospinal Fluid β-Amyloid 42 and Tau Proteins as Biomarkers of Alzheimer-Type Pathologic Changes in the Brain
Archives of Neurology · 2009 · 892 citations
The pathological process underlying Alzheimer’s disease in individuals under thirty
Acta Neuropathologica · 2010 · 803 citations
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
Science · 2002 · 13,715 citations
Neurodegenerative Diseases Target Large-Scale Human Brain Networks
Neuron · 2009 · 2,337 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.