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Regulation of MLL1 H3K4 methyltransferase activity by its core components

Nature Structural & Molecular Biology · 2006 · Vol. 13(8) · pp. 713–719
Yali DouThomas A. MilneAlexander J. RuthenburgSeunghee LeeJae Woon LeeGregory L. VerdineC. David AllisRobert G. Roeder
Epigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancerMethyltransferaseHistone methyltransferaseHistone methylationBiologyMethylationHistoneProtein subunitTransferaseEpigeneticsGenetics

MeSH terms

Cell LineDNA-Binding ProteinsHistonesHumansLysineMethylationNuclear ProteinsHistone-Lysine N-MethyltransferaseRecombinant ProteinsTranscription FactorsCatalytic DomainHeterotrimeric GTP-Binding ProteinsRNA InterferenceMultiprotein ComplexesIntracellular Signaling Peptides and Proteins
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References
The diverse functions of histone lysine methylation
Nature Reviews Molecular Cell Biology · 2005 · 2,030 citations
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