articleTop 10% cited
Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans
Journal of Hypertension · 2003 · Vol. 21(12) · pp. 2281–2286
Naomi D.L. Fisher✉(Harvard University)Meghan Hughes(Brigham and Women's Hospital)Marie Gerhard‐Herman(Hypertension Institute)Norman K. Hollenberg(Brigham and Women's Hospital)
Abstract
In healthy humans, flavanol-rich cocoa induced vasodilation via activation of the nitric oxide system, providing a plausible mechanism for the protection that flavanol-rich foods induce against coronary events.
Antioxidant Activity and Oxidative StressPhytochemicals and Antioxidant ActivitiesAdipokines, Inflammation, and Metabolic DiseasesMedicineNitric oxideVasodilationCardiologyPharmacologyInternal medicine
MeSH terms
AdolescentAdultAgedArmBeveragesBlood PressureCacaoDiastoleDose-Response Relationship, DrugEnzyme InhibitorsFemaleFlavonoidsGlucoseHumansHyperemia
Funding
- NIH Clinical Center
Citations
496
FWCI
6.87
field-weighted impact
References
31
Percentile
98%
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Cited by
Vascular protection by dietary polyphenols
European Journal of Pharmacology · 2004 · 565 citations
References
Antioxidant Activity of Dietary Polyphenols As Determined by a Modified Ferric Reducing/Antioxidant Power Assay
Journal of Agricultural and Food Chemistry · 2000 · 2,069 citations
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